Özet:

An imbalance in gut microbiota detected to serve as a predisposing factor for existence of chronic inflammation of the gastrointestinal tract, such as chronic enteropathy among cats. Given the postulation that probiotic administration might mitigate gastrointestinal disorders, its effects via rectal route have never been explored in our country among cats with chronic enteropathy. Thus the purpose of the present study was to evaluate the therapeutical efficacy of an multiple chain probiotic treatment involving Bifidobacterium combination [Bifidobacterium longum, Bifidobacterium bifidum, Bifidobacterium animalis], Lactobacillus strains [Lactobacillus rhamnosus, Lactobacillus gastricus, Lactobacillus acidophilus, Lactobacillus plantarum], Bacillus strains [Bacillus clausii, Bacillus subtilis] and a next generation probiotic Akkermansia muciniphilia via rectal route (enema)in cats with cEnT. Diagnosis was based on a) clinical, b) hematological and serum biochemical analysis along with scoring to those of Feline Chronic Enteropathy Activity Index (FCEAI). Each cat was inspected and analyzed/reevaluated and assigned a FCEAI score at the start and end of treatment for 10 day induction period. Rectal enema probiotic treatment resulted with significantly decreased composite FCEAI score (p<0.01) and laboratory parameters re-evaluation values (p<0.01) subjected to interpretation. This treatment modality without any side effects, should be subtitute other relevant treatment modalities with relapsing and degenerative effects.

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