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Amaç: Merkezi sinir sistemi infeksiyonları tüm dünyada morbidite ve mortaliteye neden olan ciddi enfeksiyonlar olup erken tanı, erken ve uygun antibiyotik tedavisi ile mortalitesi ve morbiditesi azaltılabilen bir hastalık grubudur. Ampirik antibiyotik tedavisi beyin omurilik sıvısının (BOS) mikrobiyolojik inceleme sonuçlarına göre başlanmalı, kültür antibiyogram sonuçlarına göre düzenlenmelidir. Hastanelerdeki mikroorganizmaların direnç profilinin belirli aralıklarla gözden geçirilmesi etkin tedavinin erken başlamasını sağlayabilecektir. Yöntem: Çalışma için 167 BOS kültür antibiyogram sonucu değerlendirildi. BOS kültürü alınan hastalar retrospektif olarak değerlendirilip hastaların yaşı, cinsiyeti, tanısı, uyruğu, yattığı veya başvurduğu birim, kültür örneğinin alındığı tarih ve kültür sonuçları kaydedildi. Bulgular: Kültür sonuçlarının %19,6’sında üreme varken, %81,4’ünde üreme olmadı. Kültürde üreme saptanan hastaların %41.9’nda gram negatif mikroorganizma, %51,6’sında gram pozitif mikroorganizma ve %6,4’nde mantar üremesi saptandı. En sık üreyen etken koagulaz negative stafilokoklar iken en sık BOS kültüründe üreme nedeni şant enfeksiyonları olarak belirlendi. Sonuç: Çalışmamızda üreyen mikroorganizmaların çoğu sağlık bakım ilişkili enfeksiyon etkenleri olup antibiyotik direncinin yüksek olduğu, yoğun bakım ve şant kaynaklı enfeksiyonların daha uzun süre tedavi gerektirdiği görülmüştür.
Central nervous system infections are serious infections that cause morbidity and mortality around the world and are a group of diseases that can be reduced with early diagnosis, early and appropriate antibiotic treatment and mortality and morbidity. Ampyric antibiotic treatment should be started according to the results of the microbiological examination of the brain spinal fluid (BOS), the culture should be arranged according to the results of the antibiotic. The review of the resistance profile of microorganisms in hospitals at certain intervals will be able to ensure the early start of effective treatment. Method: 167 BOS culture antibiogram results were evaluated for the study. The patients who received the BOS culture were retrospective and the patient’s age, gender, diagnosis, gender, unit where they slept or applied, the history and cultural results of the culture sample were recorded. Results: 19.6% of cultural outcomes have reproduced, while 81.4% have not reproduced. In 41.9 percent of reproductive patients in culture, gram-negative microorganisms, in 51.6 percent gram-positive microorganisms and in 6.4 percent fungi reproduction were detected. The most frequently reproductive factor of coagulase negative staphylococcus was identified as the reproductive cause in the BOS culture as chant infections. The result: Most of the microorganisms that are reproduced in our study have been found to be infection factors associated with health care, with high antibiotic resistance, intense care and chant-related infections that require longer treatment.
Objective: Central Nervous System infections is a disease group that cause morbidity and mortality all around the world, which may be prevented by early diagnosis and early, proper antibiotic treatment. Initial antibiotic treatment should be modified according to culture results and regulated according to the results of microbiological examination of cerebrospinal fluid (CSF). Furthermore, periodical scrutinization of the resistance profile of hospital microorganisms may provide early commence of effective treatment. Method: 167 CSF culture results were evaluated for this study. The patients, whose cerebrospinal fluid culture were planted, were evaluated retrospectively and age, gender, diagnosis, nationality, hospital unit that initially applied, the date of culture sample taken and culture results were recorded. Results: Reproduction was observed in 19.6% of culture results and no reproduction in 81.4%. While 41.9% had gram negative microorganism growth, 51.6% had gram positive microorganism growth and 6.4% had fungal growth of the patients with culture growth. Coagulase negative staphylococci was the most common causative agent and the most common cause of growth in CSF culture was shunt infections. Conclusion: Most of the microorganisms with culture growth was nosocomial infection factors, whereas it has been determined that infections with high antibiotic resistances and resulted from shunt and intensive care unit requires longer treatment period.
Alan : Sağlık Bilimleri
Dergi Türü : Uluslararası
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