Oxidative stress in biological systems resulting from the overproduction of free radicals is implicated in the pathogenesis of many diseases. The organism defends itself by agents called antioxidants against oxidative damage by free radicals, which show prooxidant activity. Melatonin (MEL), the chief secretory product of the pineal gland, has been shown to have in vivo and in vitro antioxidant effects other than endocrine and biological functions. Moreover, MEL is considered the most powerful antioxidant (among the others), therefore there is growing interest to MEL and also evidence showing the importance of its antioxidant action. In the present review, the antioxidative properties of MEL along with its synthesis and biological effects as well as its clinical importance are described
Alan : Sağlık Bilimleri
Dergi Türü : Ulusal
Benzer Makaleler | Yazar | # |
---|
Makale | Yazar | # |
---|