Abstract:

Metal-N-Heterosic Carbon (M-NHC) complexes have been on the forefront for many years as compounds that show catalytic activity in organometal chemistry. In recent years, studies that highlight the biological characteristics of these compounds have been very interested. Cancer is a major disease in our age and the discovery of medications to be used in the treatment is very important. Therefore, studies on the anti-cancer properties of M-NHC complexes have gained importance. M-NHC complexes based on platinum and baker, which have an anti-cancer effect, are among the most important of these complexes. With the replacement of the substitients associated with NHCs, M-NHC complexes change in anti-cancer activities. The anti-cancer mechanisms of these compounds consist of DNA mutations and reactive oxygen types (ROTs). However, M-NHC complexes will have a need for research to fully reveal the anti-cancer effects mechanisms and lead to newly synthesized complexes.

Keywords: