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  Citation Number 1
 Views 11
 Downloands 1
High performance liquid chromatographic determination of diclofenac sodium in plasma of the rat
2013
Journal:  
Iraqi Journal of Veterinary Sciences
Author:  
Abstract:

A rapid and sensitive high performance liquid chromatographic method has been developed for the determination of diclofenac sodium in rat plasma. The assay was performed after liquid-liquid extraction with 1M orthophosphoric acid and a mixture of hexane:isopropyl alcohol. Chromatographic separations were performed on C18 stationary phase with a mobile phase composed of acetonitrile: deionised water: orthophosphoric acid (45:54.5:0.5,v/v) as mobile phase with final pH of (3.5). Analytes were detected at wave length of 276nm. This method was validated for specificity and linearity with a correlation coefficient, r=0.99.

Keywords:

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Iraqi Journal of Veterinary Sciences

Field :   Sağlık Bilimleri

Journal Type :   Uluslararası

Metrics
Article : 924
Cite : 201
2023 Impact : 0.008
Iraqi Journal of Veterinary Sciences