Özet:

Introduction: The commonly used scoring system is the CHA2DS2-VASc score to determine the risk of tromboembolism in patients with atrial fibrilation. The trombocytes/lenfocytes rate (TLO) is an important indicator of inflammation specified especially in cancer patients. The aim of this study is to explore the relationship between the TLO and CHA2DS2-VASc score in patients with non-covered atrial fibrilation (KBOAF). Patients and Method: In this retrospective study, the medical records of 184 patients with non-covered atrial fibrilation (medium age 68 ± 11.4 and 51.6 percent men) who were referred to in our clinic between 2010 and 2016 were scaned retrospective. Results: The high-risk group was found to have a higher TLO, a lower left ventricular injection fraction (SVEF) and a lower number of white cells (BK) compared to the low-middle group. Although the statistical importance is low, the glomerular filtration rate (GFH) has been found lower in the high risk group. In the correlation analysis, the CHA2DS2-VASc score was found to have a weak negative correlation with the medium positive correlation (r= 0.3, p< 0.01), the medium negative correlation (r= -0.383, p< 0.01), the GFH (r= 0.235, p= 0.01) and the BK (r= 0.235, p= 0.01). In the multi-variable logistical regression analysis, the trombocytes/lenfocytes ratio and the SVEF CHA2DS2-VASc score were independent determiners. The remaining curve area in the Roc analysis is 0.61 (0.53-0) for TLO. 7, p< 0.05) and SVEF are determined as 0.69 (0.61-0.77, p< 0.001). With 65% sensitivity and 61% specificity for TLO, the high CHA2DS2-VASc score was identified as 112.5. In patients with KBOAF, we have shown that TLO is correlated with a high CHA2DS2-VASc score and that this patient group can be used as an additional and helpful parameter to the scoring system in the determination of a high risk for tromboembolism.

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