Özet:

Acute exacerbations of chronic obstructive pulmonary disease are caused by a variety of different etiologies. The aim of the current study was to determine the diagnostic biomarkers for verifying the diagnosis of acute exacerbations of chronic obstructive pulmonary disease and predicting the length of hospital stay at elderly patients. The f iles of 120 patients who had been hospitalized with the diagnose of acute exacerbation of chronic obstructive pulmonary disease between January 2017 to December 2018 in the Chest Disease Department of Gulhane Education and Training Hospital were examined retrospectively. The numbers and the percentage of male and female patients were 83 (% 69) and 37 (% 31) respectively. Increases in the prohormone brain natriuretic peptide values of elderly patients were found as statistically significant (p<0.001). Statistically significant positive correlation between the lengths of hospital stay with the prohormone brain natriuretic peptide values was found at elderly patients group (r=0.336, p=0.001). Also statistically significant positive correlation was found between high sensitive C-reactive protein values with procalcitonin and neutrophil/ lymphocyte ratio (r=0.320, p=0.001 and r=0.257, p=0.006, respectively). Our study indicates significantly higher values of prohormone brain natriuretic peptide levels at elderly patients in accordance with length of hospital stay. These results would help us to consider the use of prohormone brain natriuretic peptide levels as a diagnostic biomarker for verifying the diagnosis of acute exacerbation of chronic obstructive pulmonary disease and predicting the length of hospital stay at elderly patients.

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