Abstract:

Background: In the present study, it is aimed to determine the intervention-related change in the mean platelet volume (MPV) and platelet count in saphenous vein embolization performed using cyanoacrylate in chronic venous stasis and varicose treatment, as well as explaining the possible venous thromboembolism events. Methods: 60 patients involved in the present study were selected from the patients, who had varicose and chronic venous stasis and who applied to the Cardiovascular Surgery Polyclinic of Medical Faculty of Adıyaman University. The files of patients undergone saphenous vein embolization using CA were performed digitally and their USG and laboratory results were analyzed. Among 437 patients, 60 patients’ undergone hemogram and biochemical examination before and after the intervention were involved in the present study. The preoperative (pre-op) and postoperative (post-op) platelet counts and mean platelet volumes of the patients were analyzed. Results: When compared to the pre-op period, no significant change was observed on 1st post-ophour and 1stpost-op month (p ˃ 0.05), however the MPV value observed on the 3rd post-op day was significantly higher than the pre-op period (p ˂ 0.05). The MPV value observed on the 3rd post-op day was statistically higher than on 1st post-op hour (p ˂ 0.05) and the MPV value observed on the 1st post-op month was statistically significantly lower than on 3rd post-op day (p ˂ 0.05). Conclusion: MPV did not significantly increase from the normal values on the 1st postoperative day, whereas it significantly increased on the 3rd postoperative day. Assuming that MPV is related with the increasing thrombogenicity, it can be stated that the saphenous vein embolization by using CA that is one of the minimally invasive methods used in varicose treatment may cause thromboembolic events in the early pre-op period (in the first week).