Abstract:

Objectives: The purpose of this study was to evaluate the literature in terms of heparin-induced thrombocytopenia (HIT) that develops in COVID-19 patients. Materials and methods: Between March 2019 and March 2021, all published articles on the subject of the study formed the target population of the study. The keywords "COVID-19" or "SARS-CoV-2" and "heparin-induced thrombocytopenia" were searched in English in the most prestigious databases of PubMed, Scopus, and Web of Science (WoS). Results: No publications on this subject were found in the SCOPUS database. Only 13 publications were found in the PubMed database, and 11 in the WoS database. Eleven (78.5%) were published in 2020, and three (21.5%) were published in the first three months of 2021. There were four (28.5%) letters to the editor, six (42.8%) case reports, and one each (7.2%) correspondence, review, research article, and a short report. The only research article is also a retrospective study, except that no large case series or research article other than this one was found. The United States was identified as the country with the highest number of publications on this subject (57.1%). Conclusion: Prospective studies, we believe, are urgently needed to understand the effects of heparin-induced thrombocytopenia development on morbidity, mortality, and long-term outcomes, a condition that can contribute to COVID-19 patient mortality as well as increased risk for thromboembolic events.

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