Abstract:

Infrared metastases in breast cancer cases are assessed as stage III C according to the AJCC (American Joint Committee on Cancer) phase and are recognized as a local advanced disease. The prognostic importance of the metastasis in the breast-rhinus infrared is studied. Tools-Method: 890 cases of breast cancer in the Ankara Oncology Hospital used surgical treatment were metastases in 428 (% 48). The ac-sils metastatic events, the infraslavics were divided into two groups, with lymphatic nod metastases and non-lymphatic. Clinical and pathological parameters between the two groups were studied in the direction of local and systemic metastases. Results: In 183 of the 428 outcomes with accelerated metastases at Level I and II, there were infrared (level III) metastases (% 42.8). In the group metas-tase infraclavics; young age, premenapozal, tumor diameter large, grade load-sec, lymphatic and vein invasion, with more than metastatic lymphatic nodes 4 in the axil, extranodal invasion occurred significantly more (p<0.05). Infraclavics metastatic group with no metastases in comparison to the group with local and systematic metastases more, although the un-sick survival and overall survival rates were lower, the difference between the two groups was statistically meaningless. The result: Infraclavic metastasis found a meaningful correlation between age, menopausal condition, tumor diameter, tumor degree, lymphatic and vascular invasion, the number of aciller lymphatic tubes, extranodal invasion. It was found that the number of metastatic lymphatic nodes of the axils was an independent risk factor in terms of the metastasis of the lymphatic nodes. Keywords: Infrared lymph nod metastasis, breast cancer.     CORRELATION OF INFRACLAVICULAR METASTASIS IN BRE- AST CANCER WITH PROGNOSTIC PARAMETERS Purpose: Breast cancer patients with infraclavicular metastasis are con- sidered to have stage IIIC and locally advanced disease according to the American Joint Committee on Cancer (AJCC) TNM classification. The prognostic significance of infraclavicular metastasis in breast cancer pati- ents was evaluated. Patients and Method: Among 890 surgically treated breast cancer patients, 428 (48%) had axillary metastasis. These patients with axillary metastasis were divided into two groups: patients with and without infraclavicular lymph nod metastasis. The clinicopathological factors of these two groups were evaluated with respect to local recurrence and systemic metastasis. Results: Among the 428 patients with level I and II axillary metastasis, 183 (42.8%) had infraclavicular metastasis. Patients with young age, pre-menopausal status, large tumor size, high-grade tumor, lymphatic and vas-cular invasion, extranodal invasion and axillary lymph nod metastasis >4 were significantly higher in the infraclavicular metastasis group (p<0.05). Although local recurrences and systemic metastasis in the group with inf- raclavicular metastasis were higher, disease-free and overall survival rates were lower than those in the nonmetastatic group; these differences were not statistically significant. Conclusion: There was a significant correlation between infraclavicular lymph nod metastasis and age, menopausal status, tumor size, tumor grade, lymphatic and vascular invasion, number of axillary lymph nod metastases and extranodal invasion. The number of axillary lymph nod metastases was an independent risk factor for infraclavicular metastases. Keywords: infraclavicular lymph nod metastasis, breast cancer.