Abstract:

Cystic fibrosis (KF) is an autosomal resessive serious disease resulting from mutations in the transmembran regulator protein (KFTR) gene. Classic KF is a progressive disorder characterized by frequent respiratory infections and pancreas failure and is diagnosed in childhood. 2% of patients have a "non-classic" or "atypic" phenotype, which contains symptoms of siinfertility, acute or chronic pancreatitis, sinusitis, bronchectasis and nasal polyps. Atypical KF symptoms are usually lighter compared to typical KF and may not be found until adult age. We presented the male patient with a thirty-three-year-old diagnosis of bronchectasis, infertility and sinusitis in order to remind that the atypical KF is a disorder that affects the different organ systems in varied degrees and occurs with a wide variety of tables, and to emphasize that all specialists should keep it in mind in practice.

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