Abstract:

Aim: Hepatitis B virus (HBV) is the main cause of acute and chronic liver disease and associated with morbidity and mortality. Hepatitis B vaccine was included in the routine vaccination schedule in 1998 in our country, In this study, we aimed to evaluate the Hepatitis B markers in children born after hepatitis B vaccination was included in vaccination schedule in our country. Material and Methods: Hepatitis B markers of 310 children, between the ages of 10-19 who were admitted to Düzce University Medical Faculty Pediatric Outpatient Clinics, were evaluated. Children born after 1999 were included in the study, so that they can be considered fully vaccinated. Evaluations of the same patient at different times were excluded from the study. Results: A total of 310 children, 166 (53.5%) boys and 144 (46.5%) girls, were included in the study. Anti-HBs was positive in 192 (61.9%) of the children, and negative in 118 (38.1%). When anti-HBs and HBsAg positivity were compared in terms of gender, no significant difference was found. Conclusion: Although there is not much research today on the seropositivity of individuals after hepatitis B vaccine, we hope that the anti-HBs positivity rates found in our study will lead to plan new studies in a large population about the positivity of anti-HBs detected in the society, with considering the effect of the emergence problems such as smoking, overweight problem or vaccine transport, storage and administration of vaccines on anti-HBs positivity rates, and will ensure that the percentage reaches to desired level.

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