Özet:

Purpose: The aim of this retrospective observational study was to evaluate the safety and efficacy of transarterial chemoembolization (TACE) therapy with a mixture of bleomycin and lipiodol used in the treatment of giant liver hemangiomas. Materials and Methods: Twenty-one patients with a total of 24 giant liver hemangiomas treated with TACE using a mixture of bleomycin and lipiodol between October 2014 to January 2020 were included in this study. Dimension, volume, and compression findings prior to and after the procedure were recorded.. Results: Twenty-four hemangiomas in 21 patients (14 [66,6%] female) were statistically investigated. The median age was 47 years (min-max: 35-69 years). Post-TACE median follow-up was 26.2 months (min-max: 5.5-48.5 months). In all but two patients, a single session TACE was performed. The median dimension of giant hemangiomas was 96 mm (min-max: 41-120 mm) and 61 ml (min-max: 20-120 mm) before and after TACE respectively. Median volume was 240.79 ml (13.13-2628.62 ml) and 61 ml (3.02-831.16 ml) before and after TACE respectively. There was a statistically significant reduction in both dimension and volume. There was no major complication. Conclusion: Transarterial chemoembolization with a mixture of bleomycin and lipiodol is a safe method due to the low complication rate. Due to the fact that it significantly reduces the size of giant hemangiomas, it is an effective method. It may be an alternative in patients with giant hemangioma for whom surgical treatment is not appropriate.

Anahtar Kelimeler: