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SüleymanDemirel Üniversitesi TIP FAKÜLTESİ DERGİSİ: 2006 Haziran; 13(2) Çocukluk çağı idrar yolu enfeksiyonlarında Escherichia coli ve antibiyotik direnci Hasan Çetin, Faruk Öktem, Ahmet R. Örmeci, Birdal Yorgancıgil, Güler Yaylı Özet EGb 761.in Mannitol ve U74389F ile karşılaştırmalı olarak serebral iskemi üzerine koruyucu rolü Amaç: Çocukluk çağında idrar yolu enfeksiyonları ve antibiyotik direnci halen önemli bir sağlık sorunudur. Bu çalışmada E. coli ile gelişen idrar yolu enfeksiyonunda antibiyotik direncini ve yıllar içinde antibiyotik direncinde gelişen değişiklikleri ortaya çıkarmayı amaçladık. Yöntem: İdrar yolu enfeksiyonu olan çocukların mikrobiyolojik sonuçlarını retrospektif olarak değerlendirdik. Bulgular: İki yılda E. coli ile gelişen toplumdan kazanılmış idrar yolu enfeksiyonu olan 132 çocuk vardı. Ampisiline %79, ampisilin-sulbaktama %63.2, amoksisilin klavunata %53, ko-trimoksazole %82.2, gentamisine %6.6, netilmisine %10, amikasine %11.5, sefuroksime %21.9 ve seftriaksona %6.8 oranında direnç saptandı. Ko-trimoksazole karşı dirençte 3 yıl içinde anlamlı artış görüldü (p<0.01). Sonuç olarak çocukluk çağı idrar yolu enfeksiyonlarında periyodik olarak patojen mikroorganizmalar ve antibiyotik dirençleri değerlendirilmelidir. Antibiyotik tedavisi in vitro antibiyotik duyarlılık sonuçlarına göre kararlaştırılmalıdır. Anahtar kelımeler: İdrar yolu enfeksiyonu, antibiyotik duyarlılığı, çocukluk çağı Abstract Escherichia coli and antibiotic resistance in childhood urinary tract infections Aim: Urınary tract infections and antibiotic resistance are still a major health problem in childhood. In this study we aimed to detect the antibiotic resistance in urinary tract infection with E. coli and changing ratio in antibiotic resistance by years. Method: We evaluated the microbiologic data of children with urinary tract infection retrospectively. Results: In two years, there were 132 children with community-acquired urinary tract infection by E. coli. Antibiotic resistance were detected as 79% to ampicilline, 63.2% to ampicilline-sulbactam, 53% to amoxicillin-klavunat, 82.2% co-trimoksazole, 6.6% to gentamycine, 10% to netilmycin, 11.5% to amikacin, 21.9% to cefuroxime and 6.8% to ceftriaxone. Antibiotic resistance significantly increased to co-trimoksazole (p<0.01), in three years. In conclusion, in childhood urinary tract infection, pathogen microorganism and antibiotic resistance sould be evaluated periodically. Antimicrobial chemotherapy must be considered with result of in vitro antibiotic susceptibility tests. Key words: Urinary tract infection, antibiotic susceptibility, childhood
SuleymanDemirel University TIP FACULTY JOURNAL: June 2006; 13(2) Childhood in urinary tract infections Escherichia coli and antibiotic resistance Hasan Çetin, Faruk Öktem, Ahmet R. Örmeci, Birdal Yorgancıgil, Smiler Yaylı Summary EGb 761.in Mannitol and U74389F the protective role on cerebral ischemicals Target: Childhood in urinary tract infections and antibiotic resistance is still an important health problem. In this study, we aimed at detecting antibiotic resistance in urinary tract infection developing with E. coli and changes in antibiotic resistance developing over the years. Method: We evaluated the microbiological results of children with urinary tract infection retrospectively. In two years, E. There were 132 children with urethra infection gained from the developing community with coli. Ampisyline is resistant to 79, ampisyline-sulbactam 63.2%, amoxyline klavunate 53%, co-trimoxazole 82.2%, gentamine 6.6%, clearance 10%, amikasine 11.5%, sefuroxime 21.9%, and seftriaksine 6.8%. A significant increase in co-thrimoxazole resistance was observed within 3 years (p<0.01). As a result, pathogenic microorganisms and antibiotic resistance in childhood urinary tract infections should be periodically evaluated. Antibiotic treatment should be determined in vitro according to the results of antibiotic sensitivity. Keywords: urinary tract infections, antibiotic sensitivity, childhood Abstract Escherichia coli and antibiotic resistance in childhood urinary tract infections Aim: urinary tract infections and antibiotic resistance are still a major health problem in childhood. In this study we aimed to detect the antibiotic resistance in urinary tract infection with E. coli and changing ratio in antibiotic resistance by years. Method: We evaluated the microbiological data of children with urinary tract infection retrospectively. Results: In two years, there were 132 children with community-acquired urinary tract infection by E. coli. Antibiotic resistance was detected as 79% to ampicilline, 63.2% to ampicilline-sulbactam, 53% to amoxicilline-klavunat, 82.2% co-trimoksazole, 6. 6% to gentamycine, 10% to netilmycin, 11.5% to amikacin, 21.9% to cefuroxime and 6.8% to ceftriaxone. Antibiotic resistance significantly increased to co-trimoxazole (p<0.01), in three years. In conclusion, in childhood urinary tract infection, pathogenic microorganism and antibiotic resistance sould be evaluated periodically. Antimicrobial chemotherapy must be considered with the result of in vitro antibiotic susceptibility tests. Key words: Urinary tract infection, antibiotic susceptibility, childhood
Alan : Sağlık Bilimleri
Dergi Türü : Uluslararası
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