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 Görüntüleme 8
 İndirme 2
Evaluation of the Presence of Helicobacter Pylori in Inflammatory Bowel Disease in Children
2023
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Objective: The prevalence of Helicobacter pylori (Hp) infection in the pediatric patient group is high, but it depends on the geographical structure of the country. Many studies have show that inflammatory bowel disease (IBD) is less affected by Hp infection than the general population. We aimed to evaluate Hp infection in the IBD patient group we followed and but it depends on the geographical structure of the country. Methods: The files of the patients diagnosed with IBD who were followed-up in our outpatient clinic were retrospectively analyzed, and their diagnosis and presence of Hp in gastroscopic biopsy were recorded. Results: A total of 50 patients, 44% female (22 patients) and 56% male (28 patients) were included in the study. The mean age of the patients was 15.3 years. In the gastroscopic biopsy results of the patients, Hp was positive in gastric biopsy at a rate of 28% (14 patients). 71.4% (10 patients) of Hp-positive patients had ulcerative colitis (UC), and 21.4% (3 patients) had Chron disease (CD). When all patients were evaluated, most patients (60%) were Hp-negative (30 patients). Among patients with UC (25 patients), Hp positivity was as high as 40% (10 patients). In CD 14% (3 patients) had Hp positivity. Hp positivity was much higher in the UC patient group. No correlation was found between the presence of Hp and polymorphonuclear leukocytes/lymph ratio, mean platelet volume, acute phase markers (C-reactive protein, sedimentation), vitamin B12, and albumin levels. However, when the ferritin means were compared, the ferritin mean of the Hp-positive patients (47.4) was lower than the Hp-negative patients (62.3). Conclusion: Hp positivity was higher in the IBD patient group, particularly in patients with UC patients. Supporting the literature, Hp positivity was seen less frequently in our IBD patient group than in the general population.

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Alan :   Sağlık Bilimleri

Dergi Türü :   Uluslararası

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