Özet:

Two hundred seven newborns with indirect hyperbilirubinemia followed between February 1, 1999-August 1, 1999 were evaluated retrospectively. Etiological factors of the cases were analyzed and the rate of jaundice with unknown cause was 66.2 %. Those cases were scrutinized in respect to risk factors of the jaundice like breast-feeding, latency in the first feeding, less than 8 feedings in a day, loss of weight, delayed passage of meconium, male sexuality, use of oxytocin, mother’s age (35, parity>1, asphyxia, vacuum extraction and the influence of those factors on bilirubin level was evaluated. Forty eight percent of the cases had at least 3 risk factors at the same time. However, there was no correlation between the increase in the number of risk factors and the total bilirubin level (r=-0.067; p>0.05). The fact that 94 % of the newborns having jaundice with unknown cause are breast-fed, they have high amount of loss of weight and the occurence of jaundice in the 2nd and 3rd days in 60 % of those infants imply that there is a strong association between breast-feeding and hyperbilirubinemia. On the other hand, it was found that the case with the highest bilirubin level (51 mg/dl) was in this group and 2 cases developed kernicterus. Nowadays, although tresholds for phototherapy and exchange transfusion in the healthy term infants with hyperbilirubinemia are being moved to higher levels, risk factors should be examined carefully in those infants and the risk for bilirubin toxicity should always be kept in mind. In our study, incidence of G6PD deficiency is 3.9 %. This high rate of incidence shows that G6PD deficiency needs to be taken into consideration in etiology of hyperbilirubinemia.

Anahtar Kelimeler: