Abstract:

Background: We aimed to investigate the clinical features, hemodynamic and respiratory profiles as well as prognostic outcomes of critically sick COVID-19 patients admitted to intensive care units (ICUs). Methods: This retrospective study was performed using data derived from 99 adult patients treated in the ICU. Demographic and clinical data as well as hemodynamic and respiratory profiles, theraputic outcomes were recorded. The relationship between these features and ICU stay was sought. Results: The average age was 65.94 ± 14.93 years (24 to 96), and 73 patients (73.7%) had comorbidities. Smokers constituted 13.1% of the Covid-19 patient population (n=13) in ICU. Thirty-one cases (31.3%) had received at least one dose of Covid-19 vaccine and 63 patients (63.6%) died in the ICU after their initial hospitalization. Blood products were utilized in 29 patients (29.3%) and delta mutation was detected in 23 (23.2%) of ICU patients. The mean duration of ICU stay was 16.90 ± 11.41 days (1 to 60). The duration of ICU stay was remarkably different between groups receiving different antibiotic regimens (p<0.001). There was no significant relationship between the duration of ICU stay and blood groups (p=0.052), systolic (p=0.572) and diastolic blood pressure (p=0.098) and initial arterial oxygen saturation (p=0.223). Conclusion: We detected a high mortality rate in our series with severe COVID-19 infection treated in ICU. These data are critical for understanding the impact of COVID-19 on our hospitals, identifying areas for clinical management improvement, and allowing for continuous international and temporal comparisons of COVID-19 patient outcomes.

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