Abstract:

Objectives: Acute coronary syndrome are at the top of all causes of death in the world and in our country. In this study, we aimed to evaluate whether total blood count parameters have predictive value in the clinical course of acute coronary syndrome. Materials and Methods: The study was performed as a single center prospective study between 01.02.2017 and 31.07.2017 at the Emergency Medicine Clinic of a Training and Research Hospital in which the annual number of patients is 150,000. Ethics approval was obtained from the Local Clinical Research Ethics Committee for the study. Demographic feature, total blood count parameter, neutrophil/lymphocyte ratio (NLR), GRACE risk score of the patients were recorded. The length of stay, in-hospital mortality and 6-month mortality of the patients were followed. Results: In this study, 77.27% of the patients were male and 22.73% were female. The average age was 61 ± 12. There were significant differences between NLR's (p = 0.009) and monocyte counts (p < 0.001) in all groups in terms of in-hospital mortality. There were also significant differences between NLR's (p = 0,045) and monocyte counts (p = 0,026) in terms of 6-month mortality. There was a significant difference between the group with low NLR and the other groups in terms of hospital mortality (p = 0,006). There was no significant difference between NLR subgroups in terms of 6-month mortality in this study (p = 0.131). There was a weak correlation between GRACE score and NLR (p <0.001; rho = 0.393). Conclusion: Parameters such as total blood count and NLR in patients followed up in emergency departments due to acute coronary syndrome may help in the clinical decision making process and predicting the prognosis and mortality of patients.

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