Özet:

The purpose: in our clinic, amniyosenthesis (AS) is to evaluate the results of 217 incidents applied retrospectively. Methods: Our study included 217 cases of AS applied in our clinic between September 2011 and July 2013. The patient’s records were examined. The prognosis of pregnancies and the condition of babies, patients were reached by telephone call. A detailed ultrasound (US) examination was carried out before AS was performed. The age of pregnancies applied to AS, pregnancy, parity, abortion, the number of living children, the week of pregnancy, screening tests and anomalies detected in the US were recorded. AS indications were determined as screening test positivity, advanced mother age, maternal anxiety, previously chromosome anomaly baby birth history, foundations that reflect fetal anomaly in the US. Results: The average age of pregnancies was 32,37±6,20 (18-47), pregnancy 2,59±1,91 (0-11), parity 1,14±1,41 (0-8), abortion 0,51±0,91 (0-5), living children 1,09±1,03 (0-8) and pregnancy week 17,58±1,80 (13-27) found. The first place in the AS indications was observed with a positive triple test of 24.9%. In the 18 (8%) cases applied AS, a caryotype anomaly was detected. 6 of these caryotype anomalies are an anomalies associated with life. 4 of the phenomena identified for chromosomal anomaly were trichomy 21 (Down syndrome), 2 trichomy 18 (Edward syndrome), 2 monosomy x (Turner syndrome) and, respectively, one phenomena were trichomy 13 (Patau syndrome), trichomy 10, triploid and partial tirisomy 10 (Pallister-Killian syndrome). No chromosomal anomaly has been detected in any of the 22 cases applied to AS due to isolated advanced mother's age. In any of the cases, no abortion or fetal loss has been observed in the first three weeks after the treatment or until the date of the caryotype result. 6 of the patients (2,76) had premature births due to premature action. In three (1.30%) of our cases, intrauterine exitus was detected. After the procedure, no maternal complications were observed in any patient. The result: Chromosomal abnormalities are more often detected in the U.S. group of patients with fetal abnormalities and indications related to a number of causes. This also indicates that the abnormal scan for the purpose of prenatal diagnosis is experienced and that the subject will be more useful by the specialists. It is believed that the age of the mother alone does not increase the chance of catching the chromosomal anomaly too much.

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