Özet:

Introduction and Target: Although inflammation plays a very important role in atherosclerosis and secondary amyloidosis pathogenesis, the relationship between the two diseases is unknown. The aim of this study is to study this relationship with patients with secondary amyloidosis, by evaluating carotis intima media thickness (IMK), in non-suitable control groups. Method and Requirements: The study population consists of 14 amyloidoses with advanced inflammatory disease patients with 34 amyloidoses with undeveloped inflammatory disease patients and 34 healthy volunteers. All patients were selected from non-smoking. Patients with Aterosclerotic vascular disease and diabetes mellitus are not taken to study. Subclinical atherosclerosis B-mod ultrasound was assessed by measuring the IMK from the carotic artery and the CRP levels of all patients were measured. STATISTICally significantly, the corticosteroid BMI was measured thicker than in patients with amyloidosis (0.71±0.8 mm) and in patients with non-control (0.56±0.1 mm, p<0.001) and in healthy control group (0.43±0.4 mm, p<0.001). The C-reactive protein levels were also significantly high compared to the control groups (3.7±3.1, 1.5±1.2) (p<0.001) in amyloidosis patients (5.7±2.5). PROPOSITION AND RESULTAT: Increased IMC found in the presence of amyloidosis disease may be due to developing inflammation-related atherosclerotic changes.

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