Özet:

Purpose: Trace elements are essential for a healthy nervous system. Their levels are shown to be affected in both viral infections and febrile seizures. The aim of this study is to evaluate the serum selenium and copper levels in children with febrile seizures and viral infection. Method: This study consisted of 40 patients with simple febrile seizures and viral infection (study group) and 40 patients with fever and viral infection (control group). Serum samples were collected for selenium and copper from the study group within one hour following seizure. The serum samples were measured and compared. Results: Serum selenium levels were significantly lower in the simple febrile seizure group (p=0.043). There was no significant relation between selenium and copper levels with age, sex, body mass index, degree of fever or duration of febrile seizure.   Conclusion: Significantly decreased levels of selenium in children with simple febrile seizures may be the result of oxidative damage and the activation of antioxidant defense mechanisms. The lower serum levels of selenium in patients with SFS may trigger FS or may contribute to its recurrence. Further studies are required to assess selenium levels comparing simple and recurrent febrile seizures.  

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