Özet:

Inflammatory bowel disease are a group of chronic inflammatory disorders of unknown etiology in genetically-predisposed individuals that are characterized by chronic periods of exacerbation and remission. Two major types of inflammatory bowel disease are ulcerative colitis and Crohn's diseases. Although many clinical activity indicators and non-invasive markers are used to evaluate disease activity and treatment in these patients, none yielded results as definitive as histopathological and endoscopic investigations for determining inflammatory activity. Commonly used clinical indices to determine ulcerative colitis disease activity in inflammatory bowel disease are Truelove-Witts' Criteria and Rachmilewitz Clinical Activity Index. The Crohn's Disease Clinical Activity Index is accepted worldwide as a clinical index of Crohn's disease while among endoscopic indices, the Mayo Score for ulcerative colitis and Simple Endoscopic Score for Crohn's Disease are commonly used. In this study, we compared these widely used activity indices with laboratory parameters frequently used in our daily practice. For this purpose, we investigated the value of these parameters in clinical and endoscopic follow-up of Inflammatory Bowel Diseases.

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