Abstract:

Milk production is of great importance in the cattle cultivation. Calcium in milk is important for human health. Calcium cells are involved in many physiological events such as membrane passivity, hormone release, enzyme activity. When assessed in terms of metabolism, the need for calcium increases due to the dairy supply during the lactation period. The calcium levels are regulated by the calcium-sensitive receptor (CaSR) gene. In this study, the Damascus goats in lactation studied the relationship between them with lactation by measuring the level of expression of CaSR gene and blood calcium levels. CaSR gene expression level is measured by RT-qPCR while plasma calcium level is measured by the microplasma atomic emission spectrophotometer (MP-AES). The expression levels of CaSR genes have been significantly decreased in the 3, 5 and 7 months compared to the 1st month of breastfeeding. Compared to the 1st and 3rd months of breastfeeding, calcium levels have been significantly decreased in other months. A decrease in plasma calcium is found to be compatible with a decrease in expression levels of the CaSR gene. Thus, it has been shown that metabolism has reduced CaSR expression by creating a protective reflection to prevent the decline of calcium lost by lactation in the plasma. This study found that the loss of calcium in the laktation period in goats occurred along with milk was regulated in the blood by the CaSR gene.

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Abstract:

Milk efficiency has a big importance in goat breeding. Calcium exist in milk’s ingredient is significant for human health. Calcium takes part in many physological processes such as cell membrane permeability, oscillation of hormones, enzyme activity. The need for calcium also rises according to milk efficiency in lactation period for metabolism. Calcium is primarily organized by means of the Calcium Sensitive Receptor (CaSR) gene. In this study the relationship between the lactation and expression level of CaSR gene eith blood calcium level were evaluated in lactating Damascus goats. While CaSR expression gene was measured with RT-qPCR, plasma calcium level was measured with micro plasm atomic emission spectrophotometer (MP-AES). An important level of decline in calcium levels was found in the other months except for 1st and 3rd months. It has been found that the decline in the level of plasm calcium quantity was coherent with the decline of the expression level of CaSR. By this way it has been observed that metabolism lessens the CaSR expression by forming a protection reflex in order to prevent the falling of calcium lost with lactation. In this study, it has been found that regulation of calcium loss in blood which appears with milk of goats in lactation period is provided with CaSR gene.