Abstract:

The aim of the work. To analyze and structure the registered on market of Ukraine active pharmaceutical ingredients assortment. Materials and Methods. Methods of content analysis, structuring, comparative and graphical generalization of data from the State Register of Medicines and pharmaceutical inserts were applied. Results and Discussion. 2100 trade names of active pharmaceutical ingredients, that are manufactured in 51 countries, are registered on pharmaceutical market of Ukraine. It is established that the level of domestic ones is over 16 %, 1/5 of their total number is manufactured on JSC “Liktravy” (medicinal plant raw materials). Indian companies predominate among foreign manufacturers (29.1 %). The leaders are Hetero Drugs Limited (5.9 %) and Hetero Labs Limited (5.5 %) companies. The absence of domestic active pharmaceutical ingredients in the composition of analyzed strategically important registered drugs of Ukrainian production (blood and blood forming organs (groups B01, B02, B05 according to the ATC classification), systemic hormonal preparations (groups H01, H02), antiinfectives for systemic use (groups J01, J02, J04)) was revealed in the majority. Conclusions. The advantage of foreign synthetic active pharmaceutical ingredients with the share of 71.4 % is noted according to the results of registered on market of Ukraine active active pharmaceutical ingredients assortment analysis. Plant trade names (55.8 %), almost half of them (44.4 %) are medicinal plant raw materials, predominate among the domestic active pharmaceutical ingredients. The share of Ukrainian active pharmaceutical ingredients in the composition of studied groups of drugs is extremely small. Taking urgent measures for adjustment and optimization of production of active pharmaceutical ingredients that are components of strategically important groups of drugs, is necessary.

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