Özet:

Purpose: The purpose of this study is to study the regeneration of thrombocyte-rich fibrin (T-PRF) prepared in titanium tubes in experimentally prepared periimplantal bone defects. Tools and Methods: In the study, 12 male wistar rates were used and defects were created at a depth of 4 mm with a trephan frez of 7 mm wide on the right and left side of each rabbit. Later, 3.3x8 mm implants were placed in the tubes and periimplantal defects were restored with the Otogen greft, T-PRF, Bifasic Calcium Phosphate greft (BCP) respectively. The control group was left empty and left to spontaneous healing. After 4 weeks, all the rabbits were killed with an implant and taken the bones around them. The bone-implant connection was evaluated by the histomorfometric examination of the cuts painted with toludine blue. The outcomes: the otage group (5267,50±228,95) has increased bone implant connectivity value. However, there is no statistical difference between the autogene group and the T-PRF group (3932,50±275,50). Low BIC values have been observed in the BCP group and control group. Results: Peri-implant defects in regeneration were found in the T-PRF group with BIC values almost as much as the autogene group. Thus, T-PRF can see the role of the autogene matrix function in the future directed bone regeneration.

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