Abstract:

Purpose: Acute cholecystitis is one of the diseases that is frequently diagnosed in emergency services and general surgical clinics. The inflamation degree affects the morbidity and mortality of the disease. In this study, measuring inflammation levels, we wanted to compare the neutrophil-lenphocytes rate, the trombocytes-lenphocytes rate and the average trombocytes volume level with the classic inflammation indicators and to evaluate which values are more meaningful. Methods: Colesistectomic events in our clinic between June 2012 and December 2017 were examined retrospectively. The symptoms taken to study; the symptoms with acute cholecystitis, according to the pathological results, were divided into group 1, the symptoms with non-acute cholecystitis, and group 2. The study compared intergroup intervals, C-reactive protein (CRP), leukocyte values, neutrophil-lenfocyte ratio (NLO), thrombocyte-lenfocyte ratio (PLO), red blood cell distribution (RDW) and average thrombocyte volume levels (MPV). Results: The duration of hospitalization in Group 1 was statistically significantly longer than in Group 2 (p<0.001). There is no significant difference between the MPV and RDW values between the groups (relevantly; p=0.128, p=0.707). In Group 1, the NLO, PLO, leukocytes and CRP values were statistically significantly high compared to Group 2 (all; p<0.001). Result: In our study, in the diagnosis of acute cholecystitis, we found the RDW and MPV values not meaningful as inflammatory indicators. In acute cholecystitis, in determining the degree of inflammation; it can be said that the NLO and PLO are as meaningful as the value of leukocytes and CRP, which are the tests used in the routine.

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