Abstract:

Vitamin D is a fat soluble organic compound, acting like a hormone and playing a crucial role in calcium homeostasis in the human body. Both vitamin D and parathyroid hormone are essential in calcium metabolism. This paper aims the assessment of the current situation of vitamin D status and parathyroid hormone in Albanians, during the period of time from 2009 to 2014. All the individuals involved in this study were taken under examination through blood sampling (10 ml/person) to check for the present value of vitamin D and PTH as well as other parameters, such as calcium, phosphate, etc. PTH and vitamin D levels were measured by electrochemiluminescence immunoassay, while total calcium and phosphate values were measured by Turbidimetry method on Coobas 6000 system. The values of 25(OH) D and PTH were correlated with age, gender and electrolytes. From the results, we notice a high prevalence of vitamin D insufficiency in the group with primary hyperparathyroidism (18.15±8.75 ng/ml), low levels of vitamin D in the group with secondary hyperparathyroidism (15.71±4.45 ng/ml) and in the group with hypoparathyroidism (15.83±9.31 ng/ml). We noticed also a negative correlation between 25(OH) D and PTH levels. In conclusion, we can say that, from this study, it is noticed a high prevalence of vitamin D deficiency in Albanians, and we can recommend regular blood tests at a certain age, in order to prevent other diseases linked to low levels or insufficiency of vitamin D.

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