Abstract:

Objectives: Prostate cancer is the most seen cancer in developed country and second reason of cancer related died in this population. We evaluated the survival of the patients who had Gleason 5 patern on transrectal ultrasound guided prostate biopsy. Material and Methods: The patients who had Gleason 5 patern underwent transrectal ultrasound guided prostate biopsy between 2005-2010 years included in the study. Seventy-six patients who were followed in our policilinic or died were recorded. Age at diagnosis, time of follow, treatments, scores of Gleason, level of PSA at diagnosis and last were recorded. Results: Mean age of the patients, PSA levels, prostate volumes and following times are 69.4±8.6, 245.9±517.3 ng/ml, 57.2±30.6 cc and 38.8±12.3 months. Gleason 10.9.8 scores were detected in 6 (%7.9),68(%89.5) and 2(%2.6) patients.26 patients were treated surgical castration,44 patients were treated medical castration. Both radical prostatectomy and medical castration were performed on 6 patients. Twenty-two patients were treated with transurethral resection of prostate because of lower urinary tract symptoms. Eighteen patients died on the following days average time at 21.3±9.8 months. Conclusion: High grade prostate cancer is one of the major problems in daily practice. These patients progress to advanced stage because of the high Gleason score. High grade prostate cancer is one of the more common causes of cancer related death despite all treatments methods.

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