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Objectives: In addition to an increase in the prevalence of dialysis treatments for end-stage renal disease worldwide, the mortality rates among patients on maintenance hemodialysis remain higher than that of the general population. This study aims to evaluate factors associated with long-term survival in stable maintenance hemodialysis patients. Methods: A total of 100 patients initiating hemodialysis by February 2013 were included in this prospective cross-sectional 5-year follow-up study. Data on patient demographics, anthropometric-nutritional parameters, systolic and diastolic blood pressure levels, and hemodialysis parameters, including etiology of kidney failure, hemodialysis duration, peritoneal dialysis history, relative interdialytic weight gain (RIDWG), and Kt/V, were recorded. Results: Overall 5-year survival rate was 56.6%. The 5-year survival rate was higher in patients with younger age (71.4% below median vs. 42.0% above median, p=0.023), lower systolic (63.3 vs. 50%, respectively, p=0.005) and diastolic (62.5 vs. 51.0%, respectively, p=0.02) blood pressure levels, higher Kt/V (46.9 vs. 66.0%, respectively, p=0.044), lower RIDWG (54.0 vs. 32.7%, respectively, p=0.026), and lower serum leptin levels (63.3 vs. 50.0%, respectively, p=0.047). Cox-regression analysis revealed that only systolic blood pressure (B = 1.081, 95% CI, 0.152 to 0.756, p=0.08) was a significant risk factor for poor survival. Conclusion: Our findings revealed pre-dialysis systolic blood pressure as the sole risk factor for poor long-term survival in stable maintenance hemodialysis patients. Malnutrition-inflammation, measures of nutrition, inflammation, and anemia had no significant impact on long-term survival.
Introduction: In addition to the increased prevalence of dialytic treatments for recent renal disease worldwide, the death rates among hemodial patients continue to be higher than the general population. This study aims to assess the factors associated with long-term survival in patients with stable hemodialysis. Method: This prospective cutting five-year tracking study included a total of 100 patients who began hemodialysis after February 2013. Patient demography, anthropometric-nutrition parameters, systolic and diastolic blood pressure levels and renal insufficiency etiology, hemodialysis time, peritonal dialysis history, interdialysis weight gain and Kt/V hemodialysis parameters were recorded. The overall five-year survival rate was 56.6%. Five-year survival rate, younger age (71.4 per cent of the average and over 42.0 per cent, p=0.023), low systolic (secondly, 63.3 per cent, 50 per cent, p=0,005) and low diastolic (secondly, 62.5 per cent, 51.0 per cent, p=0.02) blood pressure, higher Kt/V (secondly, 46.9 per cent, 66.0 per cent, p=044), lower dialytic weight increase (secondly, 54.0 per cent, 32.7 per cent, p=0.026) and lower serum leptin levels (secondly, 63.3 per cent, 650 per cent, p=0.07 per cent) were higher in patients. Cox-regression analysis found that only systolic blood pressure (B=1.081, 95% GA, 0.152 to 0.756, p=0.08) was a significant risk factor for poor survival. The only risk factor for poor long-term survival in hemodialysis patients was high systolic blood pressure prior to dialysis. There is no significant impact on the long-term survival of malnutrition-inflammation, nutrition and inflammation prameters and anemia. (SETB-2021-06-187)
Alan : Sağlık Bilimleri
Dergi Türü : Ulusal
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