Özet:

Background: Septic patients may need inotropic support due to septic shock. There is no sufficient high-sensitive parameters in order to predict the need of inotropes, in septic patients. In this study, we aimed to determine the availability of shock index (SI), modified shock index (MSI) and age shock index (ASI) for the prediction of the need for inotrope usage in septic patients in intensive care units (ICU). Materials and Methods: We retrospectively evaluated the results of patients with sepsis who were hospitalized in ICU, between September 1, 2017 and December 31, 2018. We recorded age, gender, co-morbidities, acute physiology and chronic health evaluation II (APACHE II) scores, length of mechanical ventilation, length of hospital stay, inotropic support, SI, MSI and ASI. Results: Our study included 233 patients with sepsis. SI, MSI, ASI levels were found out to be statistically significantly higher in patients who did require inotropic support, compared with patients who did not receive inotropic support (p < 0.05). For SI, the area beneath the receiver operating characteristic (ROC) curve was 0.765 (95% confidence interval (CI): 0.706–0.818, p = 0.0001) and cut-off value for inotropic support was 1.06 (sensitivity: 77.2 %, 95% CI: 67.1-85.5; specificity: 70.3%, 95% CI: 62.2-77.6). For MSI, the area beneath the ROC curve was 0.753 (95% CI: 0.692–0.807, p = 0.0001) and cut-off value for inotropic support was 1.56 (sensitivity: 68.2%, 95% CI: 57.4-77.7; specificity: 70.3%, 95% CI: 62.2-77.6). For ASI, the area beneath the ROC curve was 0.707 (95% CI: 0.644–0.764, p = 0.0001) and cut-off value for inotropic support was 82.4 (sensitivity: 64.7%, 95% CI: 539–74.7; specificity: 70.3%, 95% CI: 6.22–77.6). Conclusion: Our data showed all the shock indices had mid-level prediction power for the need of inotropes.