Özet:

There are numerous studies on the effects of changing individual diet on skeletal muscle substrate utilization and there has been huge, longstanding interest to the subject. Beside, there is a growing body of effort to understand how exercise-nutrient interactions and, consequently, the glycogen stores stimulate intracellular signaling pathways. In this review, the cellular metabolic effects of the exercise performed with empty glycogen stores and the resulting adaptation periods will be discussed. Although it has been known that training with low muscle glycogen stores modulates cellular signaling pathways related to fat oxidation during submaximal exercise, it is not clear how this could be translated into exercise performance. More research determining the benefits of exercise with low glycogen stores for health and sports performance is needed. In addition, pros and cons of training with low glycogen stores should be evaluated very carefully by the athletes and coaches within the periodized training programme.

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