The process of optimizing the dissolution of colemanite ore (2CaO.3B2O3.5H2O) in methyl alcohol by CO2 in a high-pressure reactor was evaluated by using the Taguchi method. Optimum conditions for the cholemanite mineral were determined to be as follows: reaction temperature: 140°C, reaction time: 50 min, calcination time: 240 min, calcination temperature: 450 oC, solid-liquid ratio: 1/6 g.mL-1, mixing rate: 500 cycle/min, pressure: 20 bar, grain size: -100 mesh and the amount of CaCl2: 7.5 g.
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