Abstract:

Background and Aims:To examine the association between endoscopic and histological diagnoses concerning malignities of the gastrointestinal tract. Material and Methods: Two hundred thirthy one patients who underwent upper or lower gastrointestinal system endoscopy and had endoscopic biopsy were recruited retrospectively from the files of our center between the years of 2010 and 2012. The study was based on four types of endoscopic lesions including: mucosal irregularity, ulcerovegetating mass, ulcer and polyp, and four histopathological diagnoses including polyps, ulcer, gastritis and adenocarcinoma. Results:In all, 199 of 213 (86.1%) patients had gastric and duodenal biopsies and the remaining 32 (13.9%) had colonic and rectal biopsies. The average age of the patients was 63. 5 years and the average microscopic size of the lesions was 12 mm. Fifty four (23.4%) patients had histopathologic diagnosis of malignancy. Of all the lower gastrointestinal system biopsies, 59.4% were diagnosed as malignant whereas the rate was only 17.7% for upper gastrointestinal system biopsies. Conclusions:The rate of compatibility for diagnosing the malignant lesions of the gastrointestinal system between gastroenterologists and pathologists is low and the probable reasons for this discrepancy may be attributed to the experience of the endoscopist and the endoscopy tool used

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