Abstract:

It was aimed to evaluate the antibiotic susceptibilities of Gram-negative bacteria isolated from blood samples taken from pediatric patients. The samples were evaluated with the Bactec 9120 automation system bacteria were identified by the Gram-Negative ID panel using the Vitek 2 Compact (Biomerieux France) device performed with the AST N090 panel, and the results were evaluated according to The Clinical and Laboratory Standards Institute (CLSI) recommendations. Antibiotic resistance results: Ceftriaxone was the most resistant antibiotic (71.4%). Salmonella spp. it was mostly resistant to levofloxacin and ciprofloxacin (100%). While E. coli strains were the most resistant to ticarcillin and piperacillin (71.4%), the most effective antibiotics against this bacterium were imipenem and meropenem (100%). Resistance rates to all tested antibiotics were significantly higher in ESBL-producing Klebsiella spp and E coli strains than in non-ESBL-producing strains (p<0.05). Considering this information, it is vital to evaluate the current resistance profiles in the application of empirical treatment in premature and newborn patients.

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