Abstract:

Myoepithelioma accounts for less than 1% of all salivary gland tumors. It is generally located in the parotid gland, less often in the minor salivary glands of the oral cavity and in the submandibular gland. This tumor can be classified as benign or malignant on the basis of clinical and histological findings. Malignant myoepithelioma is even more rare, representing 0.2-0.45% of all salivary gland tumors. Only 27 cases with malignant myoepithelioma arising from a major salivary glands have previously been reported in the English literature. Diagnosis is based on histological and immunuhistochemical findings. Conservative surgery is the most accepted treatment choice. Radioterapy is only used when surgery is not considered feasible. In this study, a 61-year-old woman with submandibular gland malignant myoepithelioma was reported. Based on the English literature review, this case report represents the sixth case of malignant myoepithelioma of the submandibular salivary gland.

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