Özet:

Introduction and aim: Phyllodes tumour is a biphasic tumour of breast which is characterized by benign epithelial elements and cellular spindle-celled stroma. To explain different behaviour modalities of benign phyllodes tumours, we investigated the relationship of stromal and epithelial features with each other and tumour size. Material and method: There were 29 tumors from 27 patients diagnosed as benign phyllodes tumor at SSK Tepecik Teaching Hospital Pathology Department between 1995-2003. They are divided into three groups according to tumor size. Statistical comparison between three groups and among each group was made regarding stromal cellularity, stromal pleomorphism, stromal hyalinization, stromal edema, stromal vessel density and epithelial cellularity. Results: None of the histological parameters showed statistically significant differences according to tumor size. Regardless of tumor size, in benign phyllodes tumors, a positive correlation between stromal cellularity and stromal pleomorphism and a negative correlation between stromal cellularity and stromal vessel density was found (p=0.005 and p=0.028 respectively). Conclusion: Proportional increase in stromal cellularity and stromal pleomorphism and seemingly disproportional decrease in stromal vessel density may take place in predictive parameters

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