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Aim: Evaluation of choroid thickness in 2nd and 3rd trimester pregnancies by Enhanced Depth Imaging –EDI Optic Coherence Tomography (OCT).  Patients and Methods: In this study, the subfoveal, 2 mm nasal, 2 mm temporal choroidal thicknesses of both eyes in 40 pregnant and 40 non-pregnant (control) women were evaluated. The pregnant women were categorized in 2 groups, 20 being 16-24 weeks pregnant (second trimester) and 20 being 24-39 weeks pregnant (third trimester). The average age of the pregnant women and non-pregnant women was calculated as 27.4±5.8 and 26.9±7.1, respectively.  Results: The choroid thicknesses in the pregnant women were recorded by EDI-OCT as follows; right eye subfoveal 295.3±51.8μm, 2 mm nasal 242.4±49.2μm, 2 mm temporal 252.3±52.9μm and left eye subfoveal 298.4±66.7μm, 2 mm nasal 251.5±54.7μm, 2 mm temporal 263.6±64.3μm. The control group was recorded as follows; right eye subfoveal 307.8±64.5μm, 2 mm nasal 267.6±54.2μm, 2 mm temporal 292.9±50.9μm and left eye subfoveal 295.3±71.3μm, 2 mm nasal 269.6±63.7μm, 2 mm temporal 292.0±59.5μm. The comparison of the choroid thicknesses in the pregnant subjects and the control group shows that the thickness in the 2 mm nasal (p=0.032) and 2 mm temporal (p=0.001) areas of the right eye and 2 mm temporal (p=0.044) area of the left eye is significantly different. No significant difference was observed in the other areas (p>0.05)  Conclusions: In this study, choroidal thickness measurement with EDI OCT was found to be thinner in pregnant patients compared to similar age group. 

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