Özet:

In 1969, the modern breath analysis has been started. The breath of people is collected and gas chromatography (GC) has been applied to detect more than 200 different volatile organic compounds (VOCs) in breath. The difference of the VOCs amounts between healty and sick people was also detected in many other studies. So now we are able to detect diseases from breath with different techniques. One of them is the photoacoustic spectrometer (PAS). Laser photoacoustic spectroscopy (PAS) is widely used in trace gas sensing applications, which is capable of a wide dynamic range, simplicity of use, high selectivity and sensitivity This system occurs from microphone in a small cell and laser system. If optical radiation is absorbed in from a gas, it causes heating so it gives rise to thermal expansion so with absorption of radiation results with sound generation. Detection of this optically generated sound with a sensitive microphone is the basic rules for PAS system.This review study discusses clinical breath analysis with photoacoustic spectrometer and quartz-enhanced photoacoustic spectroscopy. Analysis and the results are examined. The configuration and parts of the PAS systems are described with results. The advantages and the disadvantages of the systems are investigated with analyzing other breath analysis techniques.

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