Özet:

Objective: This study was conducted to investigate factors that influence the adherence of disease-modifying therapy in Multiple Sclerosis patients. Methods: This descriptive study was conducted with 198 MS patients who meet the inclusion criteria and accepting to participate in Ege University Faculty of Medicine, Department of Neurology, MS clinic between July 2016 and February 2017. Data were collected by using Individual Identification Form prepared by the researcher that includes the sociodemographic characteristics, The Multiple Sclerosis Treatment Adherence Questionnaire (MS-TAQ), Fatigue Severity Scale, The Self Efficacy Scale and The Brief COPE. Results: Patients were adherent to therapy (59.6%) and 40.4% of patients were not adherent to therapy. Avonex were significantly more adherent then other treatments and "Memory problems" have been found the most reason of missing or forgetting medication treatment in nonadherent patients. There was a significant difference between medication adherence and some socio-demographic characteristics and characteristics of the disease. There was no significant difference between coping attitudes, fatigue and self-efficiency level and medication adherence. Conclusion: As a result, patients' adherence with medication treatment was found low and there were some social, physical and cognitive reasons affecting it.

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