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Microwave and ultrasound promoted greener synthesis of thiazolyl-pyrazoline derivatives and investigation of their biological activities
2020
Dergi:  
Journal of the Turkish Chemical Society Section A: Chemistry
Yazar:  
DOI:  
10.18596/jotcsa.563286
Özet:

Six thiazolyl-pyrazoline derivatives were synthesized starting from corresponding chalcone compounds for their antioxidant capacity and antiurease inhibitory activities. In addition to the conventional method, ultrasonic sonication and microwave irradiation methods which are environmental methods were used in the synthesis stage. Compound 2-(5-(3-bromophenyl)-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl)-4-phenyl thiazole (5a) exhibited the most potent antiurease activity with IC50 of 2,28±0,02, which was comparable to the positive control.

Anahtar Kelimeler:

0
2020
Dergi:  
Journal of the Turkish Chemical Society Section A: Chemistry
Yazar:  
DOI:  
10.18596/jotcsa.563286
Atıf Yapanlar
Bilgi: Bu yayına herhangi bir atıf yapılmamıştır.
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Journal of the Turkish Chemical Society Section A: Chemistry

Alan :   Fen Bilimleri ve Matematik

Dergi Türü :   Ulusal

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Makale : 881
Atıf : 339
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Fen Bilimleri ve Matematik Temel Alanı
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Detaylı İncele
Journal of the Turkish Chemical Society Section A: Chemistry