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Amaç: Bu çalışmada, kandidemide etkenlerin dağılımı, risk faktörleri ve olguların sağ kalımına etki eden faktörlerin incelenmesi amaçlanmıştır. Materyal ve Metot: Ocak 2016-Haziran 2019 tarihleri arasında kan kültüründe Candida türleri üreyen erişkin hastalar çalışmaya alınmıştır. Kan kültür şişeleri BACTEC FX-40 (Becton Dickinson, MD, ABD) tam otomatize kan kültür sisteminde inkübe edilmiştir. Kolonilerin tanımlanmasında Phoenix™ (Becton Dickinson Diagnostics, ABD) otomatize sistem kullanılmıştır. Hastaların klinik özellikleri hastane kayıtlarından geriye dönük olarak incelenmiştir. Bulgular: Candida türleri, 114 hastadan alınan 261 kan kültürü örneğinde saptanmıştır. Bu hastalarda, 122 kandidemi atağı tespit edilmiştir. Klinik özelliklerine ulaşılan 75 hasta incelenmiştir. Olguların %66,6’sı kadın, yaş ortalaması 74,35±14,34 yıl ve mortalite oranı %70,7 idi. Atakların %57’sinde C. albicans üredi. C. albicans ve nonalbicans Candida (NAC) üreyen olgularda, klinik bulgular ve risk faktörleri açısından istatistiksel olarak anlamlı bir fark saptanmadı. Otuz günlük sağ kalım açısından, yoğun bakım biriminde yatış, mekanik ventilasyon, bakteriyemi ve uzun yatış süresi sağ kalan grupta daha yüksek bulunmuştur. Sonuç: Kandidemi olgularının yoğun bakım biriminde izlenmesinin, hastaların sağ kalımına olumlu etki yaptığını düşünmekteyiz .
Purpose: This study aims to study the distribution of factors in candidiasis, risk factors and factors affecting the survival of events.Materials and Methods: Adult patients who reproduce Candida species in the blood culture between January 2016-June 2019 were taken to study.Blood culture bottles BACTEC FX-40 (Becton Dickinson, MD, USA) are incubated in the fully automated blood culture system.In the identification of colonies, Phoenix (Becton Dickinson Diagnostics, USA) used the automated system.™The clinical characteristics of patients have been reviewed backwards from the hospital records.Discoveries: Candida species were identified in 261 blood culture samples taken from 114 patients.In these patients, 122 candidemia attacks have been detected.75 patients have been examined with clinical characteristics. 66.6% of the cases were women, the average age was 74.35±14.34 years and the mortality rate was 70.7%. In 57% of the attacks, C. albicans was reproduced. C. albicans and nonalbicans Candida (NAC) in reproductive cases, no statistically significant differences were found in terms of clinical findings and risk factors. In terms of thirty-day survival, the intensive care unit was found higher in the surviving group as bedtime, mechanical ventilation, bacteriemia and long bedtime. The result: We consider that the monitoring of candidemia events in the intensive care unit has a positive effect on the survival of patients.
Objective: It is aimed to analyze the distribution of agents, risk factors and factors affecting survival in candidemia. Materials and Methods: We included adult patients who produced Candida spp. in the blood culture between January 2016 and June 2019 to study. Blood culture bottles were incubated in the BACTEC FX-40 (BectonDickinson, MD) fully automated blood culture system. Phoenix ™ (BectonDickinsonDiagnostics) automated system was used to identify the colonies. The clinical features of the patients were retrospectively determined from the hospital records. Results: Candida species were detected in 261 blood culture samples taken from 114 patients. In these patients, 122 attacks of candidemia were detected. 75 patients who were having clinical findings were reached. 66.6% of the cases were female, mean age was 74.35±14.34 and mortality rate was 70.7%. C. albicans growth in 57% of the attacks. There was no statistically significant difference in terms of clinical findings and risk factors in cases which C. albicans and non-albicans candida (NAC) growth. In terms of the 30-day mortality, hospitalization in intensive care unite (ICU), mechanical ventilation, bacteraemia and long hospitalization duration were found higher in the surviving group. Conclusions: We think that monitoring candidemia cases in the ICU has a positive effect on patients' survival.
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