Abstract:

Objective: It has been recently discussed that vitamin D deficiency may be associated with many serious diseases. In this study, our goal is to evaluate the levels of vitamin D of the poor population and to determine new reference intervals based on the population by indirect method. Tools and Methods: This retrospective study included patients who have applied to the Healthcare Research Hospital for approximately 2 years from July 2013 and who have been examined with a test of 25(OH)vit D. 25(OH)vitD levels were analyzed in the agreed laboratory using the Siemens ADVIA Centaur XP system using the CLIA method. The data obtained retrospectively from the laboratory information system was analyzed after being arranged according to the exclusion criteria. Patients were divided into groups according to age, gender and season. The reference range was calculated by non-parametric method. Results: When the cut-off value for vitamin D deficiency was considered to be 20 ng/ml, vitamin D deficiency was determined in 78.2% of the general population. Reference intervals determined to 5.20-35.20 ng / ml for the 2,5-97,5 percentage range were observed to be lower than the reference intervals recommended by the manufacturer company. Result: In this study, a large population in the Elazığ region assessed the levels of 25(OH)vitD. At the same time, new reference intervals have been determined, which we believe will contribute positively to clinical diagnosis and treatment. However, we believe that this work should also be done in a healthy population.

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