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 Görüntüleme 15
 İndirme 1
Pre-Operative Parameters Predicting Hemoglobin Decline Related to Percutaneous Nephrolithotomy
2022
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Şişli Etfal Hastanesi Tıp Bülteni
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Özet:

Objectives: Percutaneous nephrolithotomy (PNL) for upper urinary tract stones is a minimally invasive, effective treatment modality. Despite its high success rates, its potential complications pose a risk. In this study, we aimed to determine the risk factors associated with bleeding which is one of PNL’s most important complications. Methods: The data of patients who underwent PNL between January 2017 and December 2018 were retrospectively analyzed. The median reduction in post-operative hemoglobin levels compared to preoperative levels was found to be 1.6 g/dl, which was accepted as the threshold value. The patients with hemoglobin decrease above the threshold were assigned as Group 1, and below the threshold as Group 2. Pre-operative, perioperative data, and stone characteristics of the patients were recorded. Results: 169 patients, 85 patients in Group 1 and 84 patients in Group 2 were included in the study. The mean age of Group 1 was significantly higher (47.4±7.9 and 32±9.4 years, respectively, p=0.001) Sixteen in Group 1 (18.8%) and six in Group 2 (7, 1%) had a diagnosis of hypertension (HT) and a significant difference was found (p=0.038). The average stone burden was 2733±1121.3 mm3 in Group 1, and 2326.5±975.6 mm3 in Group 2. It was observed that there was a significantly higher stone burden in Group 1 (p=0.001). There was a significant difference between the groups in terms of mean operation time (84.4±7 and 76.2±9.9 min, respectively, p<0.001). When the complication rates were analyzed, complications were observed in 25 (29.4%) patients in Group 1 and 12 (14.2%) patients in Group 2, and a significant difference was found between both groups (p=0.019). Age and HT were found to be significant independent risk factors associated with hemoglobin decline in multivariate analyzes (p<0.001 and p<0.027, respectively). Conclusion: In this study; advanced age, presence of HT, and high stone burden were found to be predictive of reductions in hemoglobin levels. Furthermore, a correlation of decreased hemoglobin levels was detected with operative times and occurrence of complications.

Anahtar Kelimeler:

Preoperative Parameters Forecasting a Reduction of Hemoglobin Related to Percutaneous Nefrolitotomy
2022
Yazar:  
Özet:

Purpose: Percutan nefrolithotomy (PNL) is a minimal invasive, effective treatment method in the upper system calculations. Despite their high success rates, potential complications pose a risk. In this study, we aimed at identifying the risk factors associated with post-PNL bleeding, one of the most important complications. Material-Method: Data of patients who were administered PNL between January 2017 and December 2018 were retrospective. According to preoperative levels, the median decrease in postoperative hemoglobin levels was estimated at 1.6 g/dl. Patients with a decline in hemoglobin above the threshold were identified as those with a decline under Group 1. Patients’ preoperative, perioperative data and stone characteristics were recorded. Results: 169 patients were included, including 85 in Group 1 and 84 in Group 2. It was found that the age average of group 1 was significantly high (47.4 ± 7.9 and 32 ± 9.4 years respectively, p= 0.001) 16 (18.8%) in group 1 were diagnosed with hypertension (HT) in 6 (7.1%) in group 2 and a significant difference was found (p=0.038). The average stone load in Group 1 was 2733 ± 1121,3 mm3, and in Group 2 2326,5 ± 975,6 mm3. The group 1 found a significantly higher stone load (p=0,001). There was a significant difference between the groups in terms of the average operating time (84.4 ± 7 and 76.2 ± 9.9 minutes, p<0,001 respectively). When complications were studied, complications were observed in Group 1 25 (29.4%) and in Group 2 12 (14.2%) and significant differences were found between the two groups (p=0,019). In multivariant analyses, age and HT were found as a significant independent risk factor associated with a decrease in hemoglobin (respectively p<0,001, p<0,027). The result: This study found that advanced age, the presence of HT and the excess of stone load had values predicting the decline in hemoglobin. There has also been a correlation between the decrease in hemoglobin and the duration of the operation and the development of complications. (SETB-2021-03-078)

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2022
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