Özet:

Objective: To examine whether MTHFR C677T, Prothrombin G20210A and Factor V Leiden (G1691A) gene polymorphisms create a risk factor or not in young ischemic stroke patients.Materials and method: A total of 243 people under the age of 50 were included in the study 142 of whom had ischemic stroke and 101 of whom comprised the healthy control group (healthy polyclinic patients). Peripheric venous blood samples were taken from the patient and control group into EDTA tubes and genomic deoxyribonucleic acids (DNA) were obtained. Factor V Leiden, FII G20210A and MTHFR C677T polymorphisms genotyping was carried out via standard Real Time - PCR protocol. Brain imaging process was carried out on the 1st and 3rd days of the hospitalization of the patients. Statistically, chi-square, anova test and logistic regression analysis were used. Results: The study consisted of 142 (58,4%) patients with arterial ischemic stroke and 101 (41,6%) healthy controls. The MTHFR C677T mutation in arterial ischemic stroke patients was greater in comparison with the control group (p

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