Abstract:

In this study, antibacterial and antifungal effects of aerial parts and roots methanol extracts from Ferulago mughlae and Ferulago sandrasica (Apiaceae) were investigated. Kirby-Bauer disk diffusion test was utilized to detect the antibacterial and antifungal activities. All extracts only had a zone of inhibition against Staphylococcus aureus ATCC 25923 while no inhibition zone was observed in all extracts against Escherichia coli ATCC 25922, Pseudomonas aeruginosa ATCC 27853, Streptococcus pyogenes ATCC 19615 and Bacillus subtilis ATCC 6633. The inhibition zone was observed at 5000 and 2500 µg/mL dose of MeOH extracts of F. mughlae root against Bacillus cereus ATCC 117782. F. mughlae herba MeOH extracts had the inhibition zone against Haemophilus influenza ATCC 4447, except S. aureus ATCC 25923, while F. sandrasica root MeOH extract had similarly the inhibition zone against Enterococcus faecium NJ-1 ATCC. Therefore, we can conclude that these plants can be used in antimicrobial illnesses and maybe as an herbal alternative to synthetic drugs.

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