Özet:

Aim: Clinical breast examination (CBE) is important in the early diagnosis of breast cancer, especially in low- and middleincome countries. Tru-cut biopsy (TCB) is the most used method for pathological diagnosis in patients with breast mass. This study aimed to evaluate the advantages and diagnostic accuracy of TCB decision based on CBE in patients presenting with a breast mass. Material and Methods: In this prospective cohort study, the data of patients who admitted to our outpatient breast clinic between September 2020 and March 2021 were evaluated. The presenting complaints, family history, hormone replacement treatment, mass size, contour, mobility, radiological findings, BI-RADS classification, and pathological diagnosis of TCB were recorded. Two hundred- two patients who underwent TCB in our outpatient breast clinic were included in the study. Results: The presence of irregular and fixed mass was mainly observed in the malignant group compared to the benign group (67.1% vs 43.9%, P: 0.001; 75.9% vs 39%, P< 0.001, respectively). In regression analysis, age was significantly associated with breast malignancy (OR: 1.12, CI %95: 1.06-1.18). CBE showed 85.5% consistency for benign pathology, 88.5% for malignancy, and 90.2% for granulomatous breast mass. Conclusion: The patients in advanced age and postmenopausal condition with irregularly, fixed breast mass in physical examination should be considered at high risk for breast cancer. TCB should be performed by experienced surgeons in lowmiddle-income countries and the diagnosis should be reached by reducing the long time and cost caused by radiology.

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