Özet:

OBJECTIVE: Evaluation of organ functions in critically ill patients helps to predict prognosis. Scoring systems in intensive care units (ICU) play a crucial role in comparing predicted versus observed outcomes, allowing evaluation of treatment and assessment of ICU performance. Acute Physiology and Chronic Health Evaluation (APACHE) II and Sequential Organ Failure Assessment (SOFA) scores are widely used in the ICU. In our study, we aimed to evaluate the predictive value of APACHE II and SOFA scores in predicting the mortality of severe COVID-19 patients. MATERIALS AND METHODS: Severe COVID-19 patients (≥18 years old) undergoing invasive mechanical ventilation admitted to the ICU between April 1, 2020, and July 1, 2021, were retrospectively analyzed. APACHE II and SOFA scores were calculated within 24 hours after admission. The patients were divided into two groups as survived (Group 1) and nonsurvived (Group 2), and their APACHE II and SOFA scores, demographic, clinical and laboratory data were compared. RESULTS: Totally 212 patients were included. Demographic data were similar in both groups. There was no difference between APACHE II and SOFA scores (p=0.393, p=0.957, respectively). In nonsurvived group, CRP values during admission to the ICU were significantly higher (p=0.001). Conversely, positive tracheal aspirate and blood cultures were higher in survived group (p=0.023, p=0.034, respectively). CONCLUSION: APACHE II is a scoring system accepted to predict mortality in critically ill patients. However, we think that it is ineffective in predicting mortality in severe COVID-19. In these patients, the SOFA score is also ineffective in predicting the prognosis at the first ICU admission, it would be appropriate to evaluate it daily. In our study, high CRP values are associated with mortality. We think that if the scoring systems routinely used in clinical practice will be used in COVID-19 patients, it may be appropriate to add prognostic markers to these scores.

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