Özet:

Objective: In this study, it was aimed to compare clinical and laboratory characteristics of cases with mild/moderate or severe COVID-19 pneumonia and to identify factors related to severe disease. Methods: We retrospectively reviewed the clinical and laboratory characteristics of adult patients who were hospitalized with a diagnosis of COVID-19 pneumonia. The study included patients in whom SARS-CoV-2 nucleic acid was found by real-time polymerase chain reaction (RT-PCR) and pneumonia was detected chest computed tomography scan. Results: Of 94 patients (41 women, 53 men), 71 were classified as mild/moderate pneumonia while 23 were classified as severe pneumonia. Mean age was significantly higher in severe pneumonia group (p<0.001). Cough and dyspnea were most common complaints at presentation (53% and 44%, respectively). In multivariate logistic regression analysis, dyspnea (OR: 13.24; 95% CI: 1.14-153.12; p: 0.39), leukocytosis (OR: 1.29; %95 CI: 1.08-1.55; p: 0.006), CRP elevation (OR: 1.01; 95% CI: 1.00-1.02; p: 0.006) and D-dimer elevation (OR: 1.80; 95%:1.15-2.81; p: 0.01) were identified as independent factors related to severe pneumonia. Conclusion: Our results emphasized that COVID-19 pneumonia may show a severe clinical course in patients presented with dyspnea without hypoxia and had elevated leukocyte count, CRP, and D-dimer values.

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