: Amongst label-free optical sensors, those relying on silicon photonics are especially promising for the development of small-sized devices appropriate for applications at the point-of-need. In this context, our work over the last 10 years has focused on the development of silicon photonic chips that combine all optical components, both active and passive, onto the same substrate. The approach followed for this monolithic integration, as well as the application of the different silicon photonic chip versions as immunosensors for the determination of single or panels of analytes, related to biodiagnostics or the food safety sector, will be presented.
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