Abstract:

The aim of this study is to study the demographic characteristics of patients diagnosed with ectopic pregnancy in our clinic, to evaluate the success rates of medical and surgical treatment and to analyze the distribution of the frequency of ectopic pregnancy according to seasons. Instruments and Methods: Between January 2015-January 2018, 54 facts in the Trabzon Medical Park Hospital were considered retrospective and were diagnosed with ectopic pregnancy and applied to the Women's Diseases and Birth Clinic. The seasonal distribution of the frequency of ectopic pregnancies was examined based on the application dates. Demographic data of patients; age, parity status, week of pregnancy, human coronary gonodotropin (β-HCG) levels, application complaints, resume information were recorded. The identificative statistics of variables and success rates in methotrexate (MTX) treatment and seasonal distribution according to the application date were statistically analyzed in the IBM SPSS 22.0 package program environment. The relationship between the patients with ectopic pregnancy history and the patients directed to surgery was analyzed by the ki-core test. The results were statistically assessed at a 95% confidence range and a = 0.05 significance level. The average age of ectopic pregnancies was 33 ± 4.6. When all the incidents were assessed according to the coming complaints, it was frequent complaints of spine pain (%40.7) and secondary amenore (%18.5). When patients were assessed in terms of risk factors, it was seen that there were history of ectopic pregnancy and caesarean surgery. When diagnosed, 66.7% of patients (n=36) had a pregnancy week between 4-6 weeks. In addition, in 59.3% of patients (n=32) the ß-HCG values were between 5-1500 mlU/ml on MTX day. The average ß-HCG value was 609±412 mIU/ml. 85.2 percent of patients (n=46) were given a single dose of MTX and the course was provided. When the distribution of patients was examined according to seasons, the ectopic pregnancy was observed in the summer season with a ratio of 31.5% (n=17). Results: Early diagnosis of ectopic pregnancy today puts MTX treatment in the forefront. In our study, it was shown that the MTX treatment success rates in our clinic are consistent with literature. The frequency of ectopic pregnancy in the summer shows us that climate and seasonal changes have played a role in epidemicology. Keywords: Ektopic pregnancy; Methotrexate; Season distribution. The aim of this study is to evaluate the demographic characteristics of the patients who diagnosed with ectopic pregnancy in our clinic, to evaluate the success rates of medical and surgical treatment and to analyze the distribution of the incidence of ectopic pregnancies by seasons. Material and Methods: 54 patients who diagnosed as ectopic pregnancy were admitted to Trabzon Medicalpark Hospital Gynecology and Obstetrics Clinic between the dates of January 2015 and January 2018 were analyzed retrospectively. The seasonal distribution of the incidence of ectopic pregnancies was evaluated based on the application dates. The demographic dates of patients; age, parity status, gestational week, human chorionic gonodotropin (β-HCG) levels, application complaints, medical ilness history were recorded. The seasonal distribution of variables according to the application date and the success rates of methotrexate (MTX) were analyzed statistically in IBM SPSS 22.0 package program. The positive relationship between the patients with history of ectopic pregnancy and the referral to surgery was analyzed by chi-square test. Results were statistically evaluated with a 95% confidence interval and α = 0.05 significance level. Results: The average age of the patients with ectopic pregnancy was 33 ± 4.6 years. When all the cases were evaluated according to the application complaints, inguinal pain (40. 7%) and secondary amenorrhea (18.5%) were the most common complaints. When the patients were evaluated in terms of risk factors, it was seen that ectopic pregnancy and cesarean section was the most common in the medical history. The patients of 66.7% (n = 36) percent were between 4 and 6 weeks of gestation at the time of diagnosis. In addition, 59.3% (n = 32) percent of the patients had ß-HCG values on MTX day between 5-1500 mlU / ml. Average of the ß-HCG value was 609 ± 412 mIU / ml. 85.2% (n = 46) of the patients were treated with MTX successfully. When the distribution of the patients according to the seasons was examined, the rates of ectopic pregnancy was most common in 31.5% (n = 17) in summer months. Conclusion: Currently, early diagnosis of ectopic pregnancy take MTX treatment stand out. In our study, the success rates of MTX treatment in our clinic were shown to be consistent with the literature. The incidence of ectopic pregnancy in summer months suggests that climate and seasonal changes act part in epidemiology. Keywords: Ectopic pregnancy; Methotrexate; Seasonal distribution.